Adrafinil is a nootropic substance discovered in 1974 by two French chemists. Adrafinil is used to promote alertness increase attention, reduce fatigue. Adrafinil was marketed in France under the trade name Olmifon until September 2011 when it was voluntarily discontinued by manufacturer.
Adrafinil is a prodrug for modafinil. That means in the body it is metabolized into modafinil resulting in very similar pharmacological effects
Adrafinil is prohibited for in-competition use by the World Anti-Doping Agency
Benefits of Adrafinil
Adrafinil promotes alertness and wakefulness.
Adrafinil was originally created and marketed as a drug against narcolepsy.
It is important to understand the difference between drug promoting alertness/wakefulness and a general stimulant. Adrafinil does not usually cause user to feel jittery or hyperactive like caffeine. Most people describe a sense of mental clarity, increased ability to focus, or the ability to simply stay awake longer without feeling sleepy. It does not cause any high effect as other mostly stimulants
Adrafinil may increase mental acuity. Many users report feelings of heightened mental clarity. Everything from increased memory, increased reaction time, and amplified ability to focus.
Some studies on animals reported that adrafinil significantly increases their ability to learn a new task. It was shown that older dogs using adrafinil outperformed younger control group.
Another study using dogs found that adrafinil results in long-lasting increase in high frequency brain activity.
Adrafinil may improve mood.
Many users describe an increase in mood associated with an increase in mental clarity as a part of their experience with Adrafinil. Adrafinil may help to improve age related decline in cognitive abilities
Adrafinil may help to reduce fatigue and increase energy.
The exact mechanisms of the physical benefits are not known but provide interesting direction for future research.
Adrafinil may enhance memory. Some people have reported an improved memory while using adrafinil. However only one study using dogs actually found a decrease in memory in dogs given adrafinil
Adrafinil may decrease appetite.
The loss of appetite may be a benefit or a negative effect depending on your intended use.
The long-term effects of regular adrafinil use are not clear at this time.
Adrafinil may lead to the development of orofacial dyskinesia (Tardive dyskinesia) according to one case study
Some general side effects have been reported: headaches, irritability, loss of appetite and increased blood pressure, insomnia.
The recommended dosage for adrafinil is approximately 10mg/kg. This works out to approximately 600-900mg in most people.
It is important to take adrafinil early in the morning if you wish to continue a regular sleep cycle. The effects generally last somewhere between 12-15 hours.